Making your Bike into a Business

I have been recently fascinated by the opportunities for building a business around bikes--and not just bike shops, etc. Jim Gregory's book was my starting place but the video above really captured my imagination given the lack of sustainability of most modern transportation systems. Given current fuel costs, I don't know how truckers make much of a living anymore (another example of a U.S. system completely dependent on cheap fuel to make a "profit"). The fellow in the video, Brandon, was once a trucker who covered 500,000 miles per year. He now has a delivery business using a cargo bike in Chicago. I do wonder what his winter business is like (probably high demand but rougher commuting?).